Hormone Therapy and Cancer: A Clinical Perspective
Hormone therapy is a common and often effective approach in cancer treatment, particularly in cancers that are driven by hormonal signals such as prostate and breast cancers. Its role extends beyond just treatment—it is also used to alleviate symptoms and improve quality of life when other therapies are not an option.
Why Hormone Therapy Is Used
H
ormone therapy can either slow down or completely halt the growth of hormone-sensitive tumors. It can also reduce the likelihood of recurrence in certain cancers, making it both a therapeutic and preventive strategy. In cases like advanced prostate cancer, hormone therapy helps in managing symptoms when surgery or radiation are not viable.
Types of Hormone Therapy
Bl
ocking the body’s ability to produce hormones
- Interfering with how these hormones function
- The choice depends on the cancer type and treatment goals.
Cancers Treated with Hormone Therapy
Pri
marily used for prostate and breast cancers that depend on hormones to grow. It is often part of a combined treatment strategy.
When Used with Other Treatments
Befo
re surgery/radiation to shrink tumors (neoadjuvant therapy)
- After treatment to prevent recurrence (adjuvant therapy)
- To treat cancer that has returned or spread
- Side Effects
Men:
H
ot flashes
- Sexual dysfunction
- Fatigue
- Bone thinning
- Women:
Menstrual changes
- Mood swings
- Vaginal dryness
- Loss of libido
- Cost and Insurance
The co
st depends on treatment duration, type, and location. Most insurance plans cover hormone therapy, but patients should consult providers and explore financial aid if needed.
Methods of Administration
Oral (p
ills)
- Injection
- Surgical removal of hormone-producing organs (ovaries or testicles)
- Monitoring Effectiveness
Prostate
cancer: Regular PSA tests
Breast cancer: Physical exams, mammograms, lab tests
Nutrition & Weight Management
Weight ga
in may occur, especially in prostate cancer patients. A dietitian can help manage this.
— Dr. Jenan Khaledd